GHK-Cu in diabetic ulcers
Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper.
Mulder GD, Patt LM, Sanders L, Rosenstock J, Altman MI, Hanley ME, Duncan GW. · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Study record
- Population
Patients with diabetic neuropathic ulcers; sample size not in the abstract.
Inspect extraction gap · Abstract-level extractionPrimary abstract — Methods and Results- Formulation
Topical GHK-Cu gel (lamin Gel).
Read source · Abstract-level extractionPrimary abstract — Methods and Results- Route
Topical skin application.
Read source · Abstract-level extractionPrimary abstract — Methods and Results- Dose & frequency
Exact concentration/application quantity not verified; no human or KLOW regimen is inferred from this extraction.
Inspect extraction gap · Abstract-level extractionPrimary abstract; detailed regimen unavailable- Study design
Randomized, evaluator-blinded, placebo-controlled multicenter study with standardized wound care.
Read source · Abstract-level extractionPrimary abstract — Methods and Results- Duration
Exact treatment and follow-up duration not available in the abstract.
Inspect extraction gap · Abstract-level extractionPrimary abstract — Methods and Results- Reported findings
Topical treatment improved reported plantar-ulcer closure measures versus vehicle alongside standardized wound care.
Read source · Abstract-level extractionPrimary abstract — Methods and Results- Adverse events
Detailed adverse-event counts and ascertainment not available in the abstract.
Inspect extraction gap · Abstract-level extractionPrimary abstract — reporting limit- Monitoring
Full safety-monitoring schedule not verified.
Inspect extraction gap · Abstract-level extractionPrimary abstract — reporting limit
What it supports
Topical treatment improved reported plantar-ulcer closure measures versus vehicle alongside standardized wound care.
What it does not establish
Topical ulcer treatment, not systemic rejuvenation or KLOW. Full-text sample size and regimen remain unverified. Abstract-level extraction; unavailable details are explicitly flagged.
Funding
Not stated in the retrieved abstract; not evidence of no funding.
Literature search cutoff: 2026-09-08 · Not independently clinically reviewed
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