Back to profileDirect study · 2024

BPC-157 bladder-pain report

Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study.

Lee E, Walker C, Ayadi B. · Alternative therapies in health and medicine

Study record

Population

12 women, ages 39–76, with interstitial cystitis unresponsive to pentosan polysulfate.

Read source · Full-text reportPatients, p.14
Formulation

Compounded BPC-157, 2 mg/mL; pharmacy unnamed.

Read source · Full-text reportProcedure, p.14
Route

Cystoscopic injections into bladder-wall tissue.

Read source · Full-text reportProcedure, p.14
Dose & frequency

One procedure totaling 10 mg across ten sites. Not a subcutaneous recovery regimen.

Read source · Full-text reportProcedure, p.14
Study design

Uncontrolled retrospective chart review with patient-reported response assessment.

Read source · Full-text reportMethods, p.13; Results, p.14
Duration

Six-week follow-up; most later contacts occurred four to six months after treatment.

Read source · Full-text reportMethods, p.13–14; Results, p.14
Reported findings

Ten reported complete symptom resolution; two reported 80% improvement. All scored 5 on the paper’s response scale.

Read source · Full-text reportResults and Table 1, p.14
Adverse events

No adverse events or postprocedural complications reported; small retrospective ascertainment cannot establish safety.

Read source · Full-text reportResults, p.14
Monitoring

Pelvic examination, urinalysis, cystoscopy, follow-up and symptom questionnaire.

Read source · Full-text reportMethods, p.13; Patients/Results, p.14

What it supports

Describes patient-reported changes after a local procedure.

What it does not establish

No control group or causal efficacy estimate. Follow-up is not a dosing cycle. Not evidence of musculoskeletal repair or KLOW efficacy.

Funding

Patients paid for treatment; authors declared no conflicts (pp.14,16).

Literature search cutoff: 2026-09-08 · Not independently clinically reviewed

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