MGF
Mechano growth factor commonly refers to an IGF-1 splice-variant-derived C-terminal peptide. PEG-MGF is a modified product and is not an alias for the same preparation.
The short version
- Why people discuss it
- Discussed for muscle growth and recovery after training; native MGF and PEG-MGF are distinct preparations. Community interest does not establish benefit or a suitable treatment.
- What it is
- Mechano growth factor commonly refers to an IGF-1 splice-variant-derived C-terminal peptide. PEG-MGF is a modified product and is not an alias for the same preparation.
- Biggest caution
- Endogenous splice-variant biology, a synthetic C-terminal peptide and PEG-modified products are different subjects. None can automatically borrow dosing or outcomes from IGF-1 or another analog.
- Stack context
- Related profiles reflect adjacent community topics or biological context. They do not establish combination benefit, compatibility or a validated regimen.
Dose and frequency reference
Reference only — not a recommendation. Amounts describe source-specific community examples, selected study regimens or the named product label. They do not establish safety, effectiveness, product identity, or a suitable dose for any person. Never convert mg, mcg, or IU into syringe “units” without the exact product concentration.
Sources report different amounts or schedules; the reference below is a named example, not a consensus.
Native MGF — intramuscular injection
Community reference · Not clinical guidance- Amount
- 200–400 mcg
- Frequency
- 2–3 times weekly
- Duration / phase
- 4–6 weeks
Legacy native-MGF community pattern on training days. PeptideDosages instead describes daily subcutaneous dosing for 8–12 weeks. These conflicting routes and frequencies have no established human dose-finding basis. Reference only; this does not establish safety, effectiveness or individual suitability.
Reference source · reviewed 2026-09-12PEG-MGF — subcutaneous or intramuscular injection
Community reference · Not clinical guidance- Amount
- 200–400 mcg
- Frequency
- 2–3 times weekly on training days
- Duration / phase
- 4–6 weeks
Separate PEGylated preparation, not native MGF. This older community convention conflicts with PeptideDosages’ 200–500 mcg daily example for 8 weeks or longer.
Reference source · reviewed 2026-09-12Compare reported schedules
Saved source material reviewed 2026-09-27. Multiple pages from one publisher count as one source family; agreement does not establish what most people use. SC means subcutaneous; IM intramuscular; IP intraperitoneal.
- PeptideDosages — saved source reviewed September 27, 2026
Native MGF 100→300 mcg SC daily, 8–12 weeks; PEG-MGF 200→500 mcg SC daily, 8 weeks, optional longer.
Evidence & sources · Community source profile
AxonRep synthesizes community discussion signals from its internal research corpus. Individual creator sources remain attributed to the synthesis; public reference sites used in the latest comparison are linked separately. The synthesis is not clinical evidence.
- AxonRep community research synthesisAxonRep synthesis · Checked 2026-09-12
- PeptideDosages — saved source reviewed September 27, 2026Community reference · Checked 2026-09-27