AICAR
AICAR, or acadesine, is a small-molecule adenosine analog that is converted intracellularly to ZMP and can influence AMPK signaling; it is not a peptide.
The short version
- Why people discuss it
- Discussed for endurance, exercise-mimetic effects and metabolic/glucose-related goals. Community interest does not establish benefit or a suitable treatment.
- What it is
- AICAR, or acadesine, is a small-molecule adenosine analog that is converted intracellularly to ZMP and can influence AMPK signaling; it is not a peptide.
- Biggest caution
- Cell-signaling and animal-performance findings are not a human exercise protocol. Clinical acadesine research, laboratory AICAR exposure and products sold for performance use are not interchangeable.
- Stack context
- Related profiles reflect adjacent community topics or biological context. They do not establish combination benefit, compatibility or a validated regimen.
Dose and frequency reference
Reference only — not a recommendation. Amounts describe source-specific community examples, selected study regimens or the named product label. They do not establish safety, effectiveness, product identity, or a suitable dose for any person. Never convert mg, mcg, or IU into syringe “units” without the exact product concentration.
Sources report different amounts or schedules; the reference below is a named example, not a consensus.
Subcutaneous injection
Community reference · Not clinical guidance- Amount
- 10–25 mg
- Frequency
- Once daily or every other day
- Duration / phase
- 2–4 weeks
Legacy community convention. PeptideDosages instead describes 1–3 mg daily over 8 weeks; another older combination example uses 2.5–5 mg for 4–8 weeks. No established subcutaneous dose-response evidence resolves the difference. Reference only; this does not establish safety, effectiveness or individual suitability.
Reference source · reviewed 2026-09-12Compare reported schedules
Saved source material reviewed 2026-09-27. Multiple pages from one publisher count as one source family; agreement does not establish what most people use. SC means subcutaneous; IM intramuscular; IP intraperitoneal.
- PeptideDosages — saved source reviewed September 27, 2026
1→3 mg SC daily for 8 weeks; advanced up to 5 mg over 12 weeks.
Evidence & sources · Community source profile
AxonRep synthesizes community discussion signals from its internal research corpus. Individual creator sources remain attributed to the synthesis; public reference sites used in the latest comparison are linked separately. The synthesis is not clinical evidence.
- AxonRep community research synthesisAxonRep synthesis · Checked 2026-09-12
- PeptideDosages — saved source reviewed September 27, 2026Community reference · Checked 2026-09-27